yeast β- Dextran is a biologically active multiple regulator present in the cell wall of brewing yeast (S. Cerevisiea), with significant effects on immune activation. It has the functions of improving blood lipid, anti radiation, improving intestinal function, and has unique biological activity on tumor, hepatitis, cardiovascular, diabetes, anti-aging, etc. By specific treatment, improve water insoluble yeast while maintaining its original structure β- The solubility of pectin, resulting in completely water-soluble yeast β- Dextran products maintain their original biological activity and expand their application range.
yeast β- Dextran can quickly enhance the body's resistance and provide a healthy barrier for the body. And it has multiple synergistic effects such as anti infection and anti radiation. It is widely recognized as a fast immune stimulant, and according to data from over 1000 authoritative domestic and foreign journals, it has a rapid effect on improving immunity.
On May 20, 2010, the Ministry of Health issued Announcement No. 9 of 2010, approving yeast production β- Dextran as a new resource food; In 2012, the Ministry of Health approved yeast β- Glucan can serve as a nutritional enhancer and can be applied to formula milk powder for older infants; On November 24, 2011, the European Union issued Decision 2011/762/EU approving yeast β Dextran is marketed as a new food ingredient for sale; The US FDA has approved GRAS, which can be applied to various foods such as dairy products, baked goods, beverages, candies, etc.
Yeast 1, 3- β- Glucan enhance the immune defense ability of the human body by enhancing the function of macrophages and natural killer cells. It can activate macrophages, neutrophils, etc., and increase the content of white blood cells, cytokinins, and special antibodies. While comprehensively stimulating the body's immune system, it also has a very good repairing effect on damaged cells. yeast β- Dextran can quickly restore the ability of injured lymphocytes to produce cytokines (IL-1) to normal, effectively regulating the body's immune function.
Derived from yeast β- Glucan has been recognized as an effective immune modulator with significant anti infective effects. β- The main mechanism of the anti infective effect of pectin is the activation of important cytokines (IL-2, IFN)- γ， TNF- α） And enhance the phagocytic function of specialized phagocytes. Among them, phagocytic cells include macrophages, granulocytes, monocytes, and dendritic cells.
Allergic reactions are closely related to human immune function. During allergic reactions, helper T cells (Th1 and Th2 cells) play an important role in the immune system. Th1 cells mainly release inflammatory cytokines, which are responsible for activating the innate and acquired immune systems of the body when pathogens invade, in order to eliminate the invaders; Th2 cells release anti-inflammatory cytokines, mainly to eliminate inflammation after eliminating the invader, restoring the body to normal immune and physiological levels. Yeast sources 1, 3, which serve as fungal biomarkers- β- Dextran can significantly affect the immune response of helper T cells (Th1 and Th2 cells), releasing interleukin-10 (IL-10) and transforming growth factor (TGF)- β Wait for anti-inflammatory cytokines to effectively inhibit allergic reactions.
The defense mechanisms of the human lungs and respiratory tract mainly include mucus on the inner mucosa, macrophages in the alveoli, and white blood cells and immunoglobulins in the immune system. And 1, 3- β- Glucan can enhance the activity of the respiratory immune system, especially cellular immunity, thereby reducing the incidence of respiratory diseases.
yeast β- Glucan activates the body's immune system and secretes IL-2 and IFN- γ， TNF- α Wait for cytokines to achieve the function of clearing tumor cells. Studies have shown that oral administration of 1,3- β- After glucan, the macromolecular glucan is absorbed by macrophages in the gastrointestinal tract and further transferred to reticuloendothelial tissue and bone marrow.
yeast β- Dextran can reduce the insulin requirement of peripheral tissues, promote glucose to return to normal, and has obvious inhibitory and preventive effects on diabetes. β- 1,3/-1,6-glucan (specific structure) can protect and repair pancreatic islets β Cells, while regulating insulin secretion, achieve the effect of balancing blood sugar. yeast β- The high viscosity and gelling properties of pectin increase the gastric mucosal barrier effect and inhibit glucose metabolism.
Anti haze and upper respiratory tract infections
Water soluble yeast β- Dextran is prepared through a unique patented enzymatic hydrolysis technology, which can form ultrafine micelles while maintaining the integrity of its triple helix structure. This triple helix structure endows yeast with β- The excellent biological activity of pectin is further enhanced by the formation of ultrafine micelles, which enhance its solubility and stability in water. During the preparation process, carefully selected enzymes act precisely on the yeast cell wall under mild conditions, avoiding damage to the yeast cell wall β- The destruction of the structure of pectin. Therefore, water-soluble yeast β- Dextran not only maintains its original biological activity, but also becomes more easily absorbed and utilized by the human body in the form of ultrafine micelles. This innovative preparation technology is water-soluble yeast β- The application of pectin in fields such as health food, medicine, and cosmetics has opened up new possibilities.
Water dispersed yeast β- Glucan is a bioactive substance with extensive application value. In order to achieve uniform molecular weight cutting and form uniformly suspended micro micelles, we adopted advanced membrane separation technology. Through membrane separation technology, we are able to precisely control yeast β- The molecular weight distribution of pectin, removing molecules that are too large or too small, ensures that its molecular weight reaches the ideal range. This technology not only improves the purity of the product, but also preserves its biological activity. The uniformly suspended micro micelle form enables yeast to β- Dextran is easily dispersed in water, making it suitable for further applications in fields such as food, cosmetics, and medicine. Water dispersed yeast β- Glucan and chitosan form adhesive facial mask material, which has obvious advantages in the field of drug delivery. Based on the morphology design of micelles, it achieves slow and controlled release, stable structure, and can reach deep skin layers.
Carefully prepared through composite enzymatic hydrolysis technology. This technology uses a series of specially designed enzymes to specifically remove components such as chitin, mannan, and protein from the yeast cell wall, thereby highlighting the yeast β- The core value of pectin. During this process, the selectivity and activity of the enzyme are rigorously optimized to ensure precise cleavage of only the target components while maximizing preservation β- The integrity and activity of pectin. Finally, the yeast treated with composite enzymatic hydrolysis β- The formation of pectin in the form of microcapsules not only enhances its stability, but also endows it with the potential for sustained release and targeted delivery. Therefore, the complete shell type yeast β- Dextran not only has higher purity, but also has broader application prospects in fields such as food, health products, and medicine.
